Recombinant human Vesicular Acetylcholine Transporter   

Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.     

濃度：1mg/ ml

來源：Recombinant Human

純度：≥95% SDS-PAGE

表達系統(tǒng)：Escherichia coli

標簽：His tag

蛋白長度：Full length protein

內(nèi)毒素水平：<1.000 Eu/µg

純化方法：HPLC

應(yīng)用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質(zhì)期：1年

Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.

產(chǎn)品名稱：Rabbit Anti-Vesicular Acetylcholine Transporter  antibody

Rabbit Anti-Vesicular Acetylcholine Transporter  

別名：Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.    

來源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng):Human,Mouse,Rat (predicted: Rabbit)

理論分子量：57kDa

免疫原：KLH conjugated synthetic peptide derived from human Vesicular Acetylcholine Transporter

保存：-20℃
保質(zhì)期：1年

單克隆抗體

產(chǎn)品名稱：Anti-Vesicular Acetylcholine Transporter antibody

Mouse Anti-Vesicular Acetylcholine Transporter 

別名：Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.   

來源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng): Human

理論分子量：57kDa

免疫原：KLH conjugated synthetic peptide derived from human Vesicular Acetylcholine Transporter

保存：-20℃
保質(zhì)期：1年

Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.